Smoking and the Risk of Suicidal Behavior

• DOI: 10.1001/archpsyc.62.3.328
• Publication Date: 2005-03-07T16:15:45Z
• Authors: Naomi Breslau; Lonni R. Schultz; Eric O. Johnson; Edward L. Peterson; Glenn C. Davis
• Keywords: Depression; Odds; Longitudinal Study

A link between cigarette smoking and suicidal behavior has been reported in clinical epidemiological studies.To examine the association thoughts or attempt a longitudinal study, which proximate status of psychiatric disorders relation to timing behaviors is taken into account.A study young adults interviewed initially 1989, with repeated assessments over 10-year follow-up.The sample was selected from large health maintenance organization representing geographic area, except for extremes socioeconomic range. The response rate at each follow-up (3, 5, 10 years after baseline) exceeded 91%.Relative risk occurrence during intervals by start interval, estimated generalized estimating equations measures. National Institute Mental Health Diagnostic Interview Schedule used baseline reassessment.Current daily smoking, but not past predicted subsequent attempt, independent prior depression substance use (adjusted odds ratio, 1.82; 95% confidence 1.22-2.69). Additionally, current adjusting predisposition, indicated suicidality, controlling 1.74; 1.17-2.54).The biological explanation finding that associated unclear. Recent observations lower monoamine oxidase activity (which may play role central nervous system serotonin metabolism) smokers ex-smokers might provide clues, interpretations should proceed cautiously.