Wound Characteristics Among Patients Exposed to Xylazine

• DOI: 10.1001/jamadermatol.2024.4253
• Publication Date: 2024-11-13T16:33:13Z
• Authors: Lydia Lutz; Rachel McFadden; Lin Xu; Ranvir Bhatia; M. Holliday Davis; Natasa Rohacs; Jenny Wei; Jeanmarie Perrone; Margaret Lowenstein; Ashish P. Thakrar
• Keywords: Eschar; Propoxyphene

The alpha-2 agonist xylazine is increasingly detected as an adulterant in illicitly manufactured fentanyl. There concern that may be responsible for emerging pattern of necrotizing wounds among people who use drugs, but the clinical features associated with remain poorly characterized.