Use of Diabetes Technologies and Retinopathy in Adults With Type 1 Diabetes

• DOI: 10.1001/jamanetworkopen.2024.0728
• Publication Date: 2024-03-06T16:01:00Z
• Authors: T. Y. Alvin Liu; Julia Shpigel; Fatima Khan; Kerry Smith; Laura Prichett; Roomasa Channa; Sarah Kanbour; Marissa Jones; Mohammed S. Abusa...; Aniket Sidhaye; Nestoras Mathioud...; Risa M. Wolf
• Keywords: Insulin pump; Univariate analysis

Importance Diabetic retinopathy (DR) is a complication of diabetes that can lead to vision loss. Outcomes continuous glucose monitoring (CGM) and insulin pump use in DR are not well understood. Objective To assess the CGM, pump, or both, proliferative diabetic (PDR) adults with type 1 (T1D). Design, Setting, Participants A retrospective cohort study T1D tertiary center ophthalmology was conducted from 2013 2021, data analysis performed June 2022 April 2023. Exposure Use technologies, including both CGM pump. Main Measures The primary outcome development PDR. secondary progression for patients longitudinal cohort. Multivariable logistic regression models assessed PDR association use. Results total 550 were included (median age, 40 [IQR, 28-54] years; 54.4% female; 24.5% Black African American; 68.4% White), median duration 20 (IQR, 10-30) years, hemoglobin 1c (HbA ) 7.8% 7.0%-8.9%). Overall, 62.7% used 58.2% an 47.5% both; 44% (244 550) participants had at any point during study. On univariate analysis, associated lower odds PDR, (all P < .05), compared no adjusting sex, race ethnicity, duration, microvascular macrovascular complications, insurance type, mean HbA , showed (odds ratio [OR], 0.52; 95% CI, 0.32-0.84; = .008) (OR, 0.42; 0.23-0.75; .004), In without baseline 79 363 (21.8%) Conclusions Relevance this T1D, developing even after . These findings suggest may be useful management mitigate risk