Joint Distribution and Two‐Year Outcome in 347 Patients With Monoarthritis of Less Than Sixteen Weeks’ Duration

• DOI: 10.1002/acr.23334
• Publication Date: 2017-08-04T20:52:37Z
• Authors: Ellen Sauar Norli; Gina Hetland Brin...; Tore Kristian Kvien; Olav Bjørneboe; Anne Julsrud Haugen; Halvor Nygaard; Cathrine Thunem; Elisabeth Lie; Maria Dahl Mjaava...
• Keywords: Monoarthritis

Objective The present study was undertaken to investigate the joint distribution and 2‐year outcome of patients with recent‐onset monoarthritis. Methods Adult clinically apparent monoarthritis ≤16 weeks’ duration were included in a multicenter longitudinal study. Clinical characteristics, distribution, development chronic inflammatory rheumatic disease (CIRD), as well classification criteria according American College Rheumatology (ACR)/European League Against Rheumatism (EULAR) 2010 for RA studied. Predictors CIRD analyzed by multivariable logistic regression analyses. Results knee (49.3%), ankle (16.7%), wrist (14.1%) most frequently affected joints among 347 patients. A total 91 (26.2%) developed during follow‐up; 21 (6.1%) diagnosed RA, 16 (4.6%) psoriatic arthritis. Longer swelling, localization, anti–citrullinated protein antibody (ACPA) rheumatoid factor (RF) positivity independent predictors CIRD. Six 58 (10.3%) 49 (42.9%) follow‐up. ACR/EULAR Criteria identified all seropositive at an early stage, mostly within 3 months. Conclusion Approximately one‐fourth over 2 years. Patients presenting arthritis rarely CIRD, whereas more did so. swelling ACPA RF also predictive Our findings facilitate identification who have unfavorable prognosis.