Zirconium‐Based Metal‐Organic Framework Capable of Binding Proinflammatory Mediators in Hydrogel Form Promotes Wound Healing Process through a Multiscale Adsorption Mechanism

• DOI: 10.1002/adhm.202301679
• Publication Date: 2023-11-07T01:25:36Z
• Authors: UnJin Ryu; Pham Ngoc Chien; Suin Jang; Xuan‐Tung Trinh; Hyeon Shin Lee; Le Thi Van Anh; Xin Rui Zhang; Nguyen Ngan Giang; Nguyen Van Long; Sun‐Young Nam; Chan Yeong Heo; Kyung Min Choi
• Keywords: Proinflammatory cytokine

The regulation of proinflammatory mediators has been explored to promote natural healing without abnormal inflammation or autoimmune response induced by their overproduction. However, most efforts control these have relied on pharmacological substances that are directly engaged in biological cycles. It is believed functional porous materials removing target provide a new way the process using adsorption mechanisms. In this study, Zr-based metal-organic frameworks (MOF)-808 (Zr