Design of Multifunctional Micelle for Tumor‐Targeted Intracellular Drug Release and Fluorescent Imaging

• DOI: 10.1002/adma.201104066
• Publication Date: 2011-12-06T07:36:25Z
• Authors: Weiwei Wang; Du Cheng; Faming Gong; Xiangmin Miao; Xintao Shuai
• Keywords: Surface Modification

A novel multifunctional polymeric micelle bearing a pH-tunable on-off module for programmed drug release, folate tumor targeting, and quantum dots fluorescent imaging is described. The can turn release off at neutral pH whereas on inside lysosomes. QD functionalization allows clear elucidation of facile visualization in vivo delivery event. Detailed facts importance to specialist readers are published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted by the authors. Please note: publisher responsible content functionality any supporting information supplied Any queries (other than missing content) should be directed corresponding author article.