An Imagable and Photothermal “Abraxane‐Like” Nanodrug for Combination Cancer Therapy to Treat Subcutaneous and Metastatic Breast Tumors

• DOI: 10.1002/adma.201404308
• Publication Date: 2014-12-12T11:37:05Z
• Authors: Qian Chen; Chao Liang; Chao Wang; Zhuang Liu
• Keywords: Indocyanine Green

A new "Abraxane-like" nanotheranostic formulation self-assembled from three clinically approved agents, human serum albumin, paclitaxel, and indocyanine green, is developed. Utilizing such a newly formulated nanodrug, combined photothermal chemotherapy conducted under the guidance of imaging, not only effectively eliminating subcutaneous tumors, but also significantly inhibiting development metastatic tumors in this proof-of-concept study. As service to our authors readers, journal provides supporting information supplied by authors. Such materials are peer reviewed may be re-organized for online delivery, copy-edited or typeset. Technical support issues arising (other than missing files) should addressed Please note: The publisher responsible content functionality any Any queries content) directed corresponding author article.