Mutant KRAS Drives Immune Evasion by Sensitizing Cytotoxic T‐Cells to Activation‐Induced Cell Death in Colorectal Cancer

• DOI: 10.1002/advs.202203757
• Publication Date: 2023-01-05T02:13:00Z
• Authors: Huashan Liu; Zhenxing Liang; Sijing Cheng; Liang Huang; Wenxin Li; Chi Zhou; Xiaobin Zheng; Shujuan Li; Ziwei Zeng; Liang Kang
• Keywords: Evasion (ethics)

The roles of oncogenic KRAS in tumor immune evasion remain poorly understood. Here, mutant is identified as a key driver colorectal cancer (CRC). In human CRC specimens, significant reduction cytotoxic CD8