Surface Functionalization of Hydroxyapatite Scaffolds with MgAlEu‐LDH Nanosheets for High‐Performance Bone Regeneration

• DOI: 10.1002/advs.202204234
• Publication Date: 2022-11-17T09:41:26Z
• Authors: Guanyun Wang; Zehui Lv; Tao Wang; Tingting Hu; Yixin Bian; Yu Yang; Ruizheng Liang; Chaoliang Tan; Xisheng Weng
• Keywords: Surface Modification

Although artificial bone repair scaffolds, such as titanium alloy, bioactive glass, and hydroxyapatite (HAp), have been widely used for treatment of large-size defects or serious destruction, they normally exhibit unsatisfied efficiency because their weak osteogenic angiogenesis performance well poor cell crawling adhesion properties. Herein, the surface functionalization MgAlEu-layered double hydroxide (MAE-LDH) nanosheets on porous HAp scaffolds is reported a simple effective strategy to prepare HAp/MAE-LDH enhanced regeneration. The MAE-LDHs scaffold can significantly improve its roughness, specific surface, hydrophilicity, thus effectively boosting cells differentiation. Importantly, grown enable sustained release Mg