Transition‐Metal‐Free Intramolecular Carbene Aromatic Substitution/Büchner Reaction: Synthesis of Fluorenes and [6,5,7]Benzo‐fused Rings

• DOI: 10.1002/anie.201409982
• Publication Date: 2015-01-21T12:43:05Z
• Authors: Zhenxing Liu; Haocheng Tan; Long Wang; Tianren Fu; Ying Xia; Yan Zhang; Jianbo Wang
• Keywords: Electrophilic aromatic substitution; Substitution (logic); Substitution reaction

Abstract Intramolecular aromatic substitution and Büchner reaction have been established as powerful methods for the construction of polycyclic compounds. These reactions are traditionally catalyzed by Rh II catalysts with α‐diazocarbonyl compounds substrates. Herein a transition‐metal‐free intramolecular substitution/Büchner is presented. use readily available N ‐tosylhydrazones diazo compound precursors show wide substrate scope.