Biomedical potential of hydrothermally synthesized zinc oxide nanoparticles for antifungal evaluation and cytotoxicity analysis

• DOI: 10.1002/aoc.7270
• Publication Date: 2023-10-04T09:07:58Z
• Authors: Geetika Guleria; Sahil Kumar; Sapna Thakur; Dhananjay K. Sharma; Shweta Thakur; Susheel Kalia; Mamta Shandilya
• Keywords: Aspergillus niger

As nanotechnology gains popularity in medicine, there is a growing concern that small nanoparticles (NPs) could accumulate and penetrate deep into the human body, posing potential risks to various organs. To ensure safe usage assess hazards, it crucial conduct toxicological evaluation of ZnO NPs on organs such as kidney. The present study involved synthesis by using hydrothermal method. Pure crystalline phase was confirmed X‐ray diffraction (XRD). SEM images displayed less agglomerated surface morphology, implying were distributed relatively evenly exhibited plate‐like shape. Two pathogenic fungi Fusarium incarnatum Aspergillus niger isolated from capsicum tomato, respectively, identified through morphological molecular analysis. antimycotic property synthesized examined against Fusariumincarnatum (MT682502) (MT675916) showed decreased microbial growth after 9 days incubation. embryonic kidney (HEK293) cell line 88% viability with 10 μg/ml, leading use NPs.