Randomized clinical trial of the effects of preoperative and postoperative oral nutritional supplements on clinical course and cost of care

• DOI: 10.1002/bjs.4578
• Publication Date: 2004-06-02T18:58:07Z
• Authors: F Smedley; T Bowling; M James; E Stokes; C Goodger; O O'Connor; C Oldale; P Jones; D Silk
• Keywords: Nutritional Supplementation

Postoperative oral nutritional supplementation has been shown to be of clinical benefit. This study examined the effects and cost administration supplements both before after surgery.This was a randomized trial conducted in three centres. Patients undergoing lower gastrointestinal tract surgery were one four groups: group CC received no supplements, SS took surgery, CS postoperative only, SC given only surgery. Preoperative from time it decided operate 1 day started when patient able take free fluids continued for 4 weeks discharge hospital. Data collected included weight change, complications, length stay, intake, anthropometrics, quality life detailed costings covering all aspects care.Some 179 patients randomized, whom 27 withdrawn 152 analysed (CC 44, 32, 35, 41). Dietary intake similar groups throughout study. Mean energy preoperative 536 542 kcal/day respectively; that 2 hospital 274 361 respectively. There significantly less loss than (P < 0.050), fewer minor complications 0.050). differences rate major anthropometrics life. overall costs greatest group, although between not significant.Perioperative admission diminished degree incidence cost-effective.