EXAFS and FTIR studies on the binding of deoxycholic acid with copper and zinc ions

• DOI: 10.1002/bspy.350010407
• Publication Date: 2005-05-31T11:43:21Z
• Authors: W. D. Huang; T. D. Hu; Q. Peng; R. D. Soloway; S. F. Weng; J. G. Wu
• Keywords: Deoxycholic acid

Abstract Deoxycholic acid is an important physiological bile acid. The binding of salts with metal ions has received more attention due to its clinical significance. In this study, a series copper and zinc deoxycholate complexes were synthesized. EXAFS FTIR spectroscopic techniques used for characterization. results indicated that both the carboxyl hydroxyl groups deoxycholic are Cu (or Zn) ion form new complex. There six oxygen atoms surrounding average bond lengths Cu‐O Zn‐O 1.95 2.06 Å respectively. © 1995 John Wiley & Sons, Inc.