Histopathological findings of new in-stent lesions developed beyond five years

• DOI: 10.1002/ccd.20787
• Publication Date: 2006-09-12T21:28:21Z
• Authors: Katsuyuki Hasegawa; Hideo Tamai; Eisho Kyo; Kunihiko Kosuga; Shigeru Ikeguchi; Tatsuhiko Hata; Masaharu Okada; Shinya Fujita; Takafumi Tsuji; Shinsaku Takeda; Rei Fukuhara; Yuetsu Kikuta; Seiichiro Motohara; Kazuo Ono; Eiji Takeuchi
• Keywords: Atherectomy; Bare metal; Bare-metal stent; Target lesion

We analyzed 14 cases of new lesions inside implanted bare-metal stents. In every case, there was no angiographic restenosis within 3 years, but a lesion observed stented segment at long-term follow-up (>5 years). Fourteen were evaluated: 9 with Wiktor stents, 2 Palmaz-Schatz and ACS Multilink The interval from stent implantation to angiography 63-147 months (89 +/- 23). Thirteen treated by percutaneous coronary intervention (PCI) stenotic tissue obtained directional atherectomy (DCA) in 10 cases. All retrieved samples composed newly developed atherosclerosis facing the healed neointimal layer, four showed histopathological findings acute syndrome. Stent struts inflammation surrounding them. Qualitative quantitative analysis performed two that metal corrosion. These suggest atherosclerotic progression occurred without peristrut inflammation.