The impact of organized mammography service screening on breast carcinoma mortality in seven Swedish counties

• DOI: 10.1002/cncr.10765
• Publication Date: 2002-10-06T11:53:08Z
• Authors: Stephen W. Duffy; Laszlo Tabár; Hsiu‐Hsi Chen; Marit Holmqvist; Ming‐Fang Yen; Shahim Abdsalah; Birgitta Epstein; Ewa Frodis; Eva Ljungberg; Christina Hedborg...; Ann Sundbom; Maria Tholin; Mika Wiege; Anders Åkerlund; Hui‐Min Wu; Tao‐Shin Tung; Yueh‐Hsia Chiu; Chen‐Pu Chiu; Chih‐Chung Huang; Robert A. Smith; Måns Rosén; Magnus Stenbeck; Lars Holmberg
• Keywords: Screening mammography; Breast carcinoma; Mammography screening

The evaluation of organized mammographic service screening programs is a major challenge in public health. In particular, there need to evaluate the effect program on mortality breast carcinoma, uncontaminated epoch by from 1) cases diagnosed prescreening period and 2) among unscreened women (i.e., nonattenders) after initiation screening.In current study, authors ascertained carcinoma deaths epochs 7 Swedish counties tumors these age group 40-69 years 6 50-69 1 county. Data regarding were obtained Uppsala Regional Oncologic Center conjunction with National Cause Death Register. total number eligible range living each county was annual population data Statistics Sweden. Detailed provided centers seven counties, including invited, attended, whether individual case exposed (screen-detected interval combined) or unexposed (not-invited screening. There 2044 14,092 incident epochs, person-years 7.5 million. analyzed using Poisson regression corrections for self-selection bias lead-time when appropriate.The reduction all combined actually compared 44% (relative risk [RR] = 0.56; 95% confidence [95% CI], 0.50-0.62). When considered, both those combined, > 10 found demonstrate significant 32% (RR 0.68; CI, 0.60-0.77) < showed 18% 0.82; 0.72-0.94) epoch. Within epoch, adjustment bias, 39% 0.61; 95%CI, 0.55-0.68) observed association invitation screening.Organized covering approximately 33% Sweden, resulted 40-45% screened. policy offering associated 30% invited population, combined. results study indicate that majority indeed due