Postbiotics: Enhancing human health with a novel concept

• DOI: 10.1002/efd2.180
• Publication Date: 2024-08-29T09:54:38Z
• Authors: Mingzhi Da; Jun Sun; Chen Ma; Daotong Li; Li Dong; Li‐Shu Wang; Fang Chen
• Keywords: 0303 health sciences; 03 medical and health sciences; gut microbiota; RA1190-1270; postbiotic; prebiotic; Toxicology. Poisons; TP368-456; functional foods; metabolites; probiotic; Food processing and manufacture

Abstract Postbiotics is a novel category of biotics that encompasses dead cells, metabolites, and derivatives from gut microbiota. These substances can exhibit their effects without containing such as in cell‐free supernatants spent media. Examples widely studied postbiotics include short‐chain fatty acids, exopolysaccharides, cell wall fragments, bacterial lysates. Evidence suggests have numerous benefits for human health, including antiaging, anti‐inflammatory properties, participation immune lipid metabolism regulation. Specifically, improve intestinal health by strengthening the barrier, reducing inflammation, promoting antibacterial activity. findings may pave way development postbiotic functional foods future. This review provides an overview components, effects, industrial applications postbiotics, aiming to consolidate existing research conclusions serve reference future studies.