Preoperative transarterial chemoembolization and resection for hepatocellular carcinoma: A nationwide Taiwan database analysis of long‐term outcome predictors

• DOI: 10.1002/jso.23521
• Publication Date: 2013-11-30T20:02:38Z
• Authors: Hon‐Yi Shi; Shen‐Nien Wang; Shih Chin Wang; Shih‐Chang Chuang; Chun‐Min Chen; King‐Teh Lee
• Keywords: Adult; Male; Carcinoma, Hepatocellular; Databases, Factual; Liver Neoplasms; Confounding Factors, Epidemiologic; Kaplan-Meier Estimate; Middle Aged; Hepatitis B; Hepatitis C; Disease-Free Survival; Hospitals; Neoadjuvant Therapy; 3. Good health; 03 medical and health sciences; Hepatic Artery; 0302 clinical medicine; Predictive Value of Tests; Hepatectomy; Humans; Female; Chemoembolization, Therapeutic; Aged

Background To explore long‐term predictors of outcome after TACE and resection in a population patients with hepatocellular carcinoma (HCC). Methods A total 648 had received before liver (TACE group) while 10,431 without (LR group). Propensity scores were calculated by entering the patient data into logistic regression model for predicting HCC outcomes. Results Compared to LR group, group did not significantly differ disease‐free survival (DFS) (median, 17 months vs. 13 group; P = 0.410) overall‐survival (OS) 56 54 0.777). The also showed that gender, cirrhosis, CCI score, hospital volume, surgeon volume independently associated DFS score level DFS/OS. Conclusions This population‐based cohort study provides compelling evidence preoperative does reduce or OS resectable HCC. Moreover, outcomes these procedures are characteristics characteristics. Medical professionals health care providers should carefully evaluate candidates J. Surg. Oncol. 2014 109:487–493 . © 2013 Wiley Periodicals, Inc.