Efficacy and Influence Factors of 308‐nm Excimer Lamp with Minoxidil in the Treatment of Alopecia Areata

• DOI: 10.1002/lsm.23210
• Publication Date: 2020-01-10T04:05:46Z
• Authors: Anqi Li; Xianfu Meng; Xiaojing Xing; Hong Tan; Junlian Liu; Chengxin Li
• Keywords: Minoxidil; Erythema; Excimer

Background and Objectives Alopecia areata (AA) is an autoimmune disease characterized by T cell‐mediated attack on the hair follicle. Although there are a wide range of therapies, majority them not satisfactory due to side effects or limited efficacy. In this study, we sought evaluate efficacy, influence factors, safety 308‐nm excimer lamp with minoxidil in treatment AA. Study Design/Materials Methods This was prospective, single‐blinded, self‐control using for One selected alopecia lesion divided into control treated side. Topical (2% solution) used both sides, but only added The primary endpoint discrepancy growth each Results A total 38 patients (24 males 14 females) AA were enrolled 34 (21 13 completed whole treatment. Thirty‐two (94.2%) achieved clinical response, 21 (44.1%) >50% regrowth after 12‐week number diameter had significantly increased compared statistical differences. Hyperpigmentation erythema occurred all they considered tolerable. Patients younger age smaller area better effect. Conclusions therapy can be as effective safe single multiple Lasers Surg. Med. © 2020 Wiley Periodicals, Inc.