Do medication prescription patterns follow guidelines in a cohort of women with interstitial cystitis/bladder pain syndrome?

• DOI: 10.1002/nau.24923
• Publication Date: 2022-04-07T22:33:31Z
• Authors: Lauren N. Tholemeier; Catherine Bresee; Amanda M. De Hoedt; Kamil E. Barbour; Jayoung Kim; Stephen J. Freedland; Jennifer T. Anger
• Keywords: Bladder Pain Syndrome; Depression

Abstract Objective To describe prescription prevalence of oral bladder pain medications among women with interstitial cystitis/bladder syndrome (IC/BPS) and to compare current treatment guidelines. Methods We sampled female patients an ICD‐9/10 diagnosis IC/BPS (595.1/N30.10) by querying active users the Veterans Health Administration. Medical records were reviewed determine whether met diagnostic criteria. A cohort other pelvic disorders was identified. Prescription typical non‐narcotic compared between two groups healthy controls. also before after made using Poisson regression. Results There 641 who criteria for 197 “Other pain” disorders. Women prescribed a medication more often than those (77% vs. 59%, p < 0.0001). Of IC/BPS, 44% tried three or medications. only 67% American Urological Association‐recommended medication. increased both pentosan polysulfate (10%–29%, 0.0001) hydroxyzine (17%–40%, 0.0001), but not amitriptyline cimetidine. Amitriptyline 223 125 which (56%) had documented history depression. Conclusions Many required multiple prescriptions, highlighting difficulty in finding effective IC/BPS. Pentosan preferred Our next step will be analyze patterns did receive