Association of Obesity with Disease Severity Among Patients with Coronavirus Disease 2019

• DOI: 10.1002/oby.22859
• Publication Date: 2020-04-30T19:08:36Z
• Authors: Markos Kalligeros; Fadi Shehadeh; Evangelia K. Mylona; Gregorio Benitez; Curt G. Beckwith; Philip A. Chan; Eleftherios Mylon...
• Keywords: Adult; Male; Endocrinology, Diabetes and Metabolism; Pneumonia, Viral; Medicine (miscellaneous); Severity of Illness Index; Betacoronavirus; 03 medical and health sciences; Endocrinology; 0302 clinical medicine; Odds Ratio; Prevalence; Humans; Obesity; Pandemics; Retrospective Studies; 2. Zero hunger; Nutrition and Dietetics; SARS-CoV-2; COVID-19; Middle Aged; Respiration, Artificial; 3. Good health; Hospitalization; Intensive Care Units; Logistic Models; Female; Coronavirus Infections

Objective The aim of this study was to explore the potential association obesity and other chronic diseases with severe outcomes, such as intensive care unit (ICU) admission invasive mechanical ventilation (IMV), in patients hospitalized coronavirus disease 2019 (COVID‐19). Methods This analyzed a retrospective cohort 103 COVID‐19. Demographic data, past medical history, hospital course were collected analyzed. A multivariate logistic regression analysis implemented examine associations. Results From February 17 April 5, consecutive Among them, 44 (42.7%) admitted ICU, 29 (65.9%) required IMV. prevalence 47.5% (49 103). In analysis, (BMI ≥ 35 kg/m 2 ) associated ICU (adjusted odds ratio [aOR]: 5.39, 95% CI: 1.13‐25.64). Moreover, who IMV more likely have had heart (aOR: 3.41, 1.05‐11.06), = 30‐34.9 ; aOR: 6.85, 1.05‐44.82), or 9.99, 1.39‐71.69). Conclusions our admission, whereas history 30 independently use Increased vigilance aggressive treatment COVID‐19 are warranted.