Eugenia punicifolia (Kunth) DC. as an Adjuvant Treatment for Type‐2 Diabetes Mellitus: A non‐Controlled, Pilot Study

• DOI: 10.1002/ptr.5206
• Publication Date: 2014-08-06T14:34:10Z
• Authors: Débora Simone Sales; Fabio Carmona; Bruna Cestari de ...; Silvia Helena Tal...; Ana Carolina Duó ...; Fernando B. Honorato; Edson Z. Martinez; Ana Maria Soares ...
• Keywords: Blood Glucose; Glycated Hemoglobin; Male; 0301 basic medicine; Syzygium; Pilot Projects; Middle Aged; 3. Good health; Plant Leaves; 03 medical and health sciences; C-Reactive Protein; Diabetes Mellitus, Type 2; Humans; Insulin; Female; Aged; Phytotherapy

Type‐2 diabetes mellitus (DM) is a highly prevalent disease with significant morbidity and mortality around the world. However, there no universally effective treatment, because response to different treatment regimens can vary widely among patients. In this study, we aimed investigate whether use of powdered dried leaves Eugenia punicifolia (Kunth) DC. (Myrtaceae) as an adjuvant patients type‐2 DM. Fifteen were enrolled in pilot, non‐controlled received E . for 3 months. After observed decrease glycosylated hemoglobin, basal insulin, thyroid‐stimulating hormone, C‐reactive protein, both systolic diastolic blood pressure. There changes fasting postprandial glycemia. The compounds myricetin‐3‐ O ‐rhamnoside, quercetin‐3‐ ‐galactoside, ‐xyloside, kaempferol‐3‐ phytol, gallic acid, trans‐caryophyllene present may be responsible therapeutic effect. conclusion, are promising DM deserve further investigation. Copyright © 2014 John Wiley & Sons, Ltd.