OC14.03: Intrapulmonary artery Doppler predicts mortality in non‐severe left‐sided congenital diaphragmatic hernia

• DOI: 10.1002/uog.22304
• Publication Date: 2020-10-16T05:36:31Z
• Authors: D. Basurto; J. Fuenzalida; A. Pertierra; R.J. Martinez‐Por...; F.M. Russo; J. Martínez; J. Deprest; E. Gratacós; O. Gómez
• Keywords: 03 medical and health sciences; 0302 clinical medicine

We aimed to investigate in non-severe left-sided congenital diaphragmatic hernia (nsLCDH): The correlation between intrapulmonary artery Doppler (IPaD) and survival; Whether the IPaD could improve current algorithm; correlates with morbidity. Retrospective analysis on expectantly managed nsLCDH [(observed-to-expected-lung-to-head-ratio)o/eLHR>25%] at BCNatal (2008-2019). Primary outcome was survival. Predictors of survival were o/eLHR, liver herniation, gestational age birth. Correlation presence persistent pulmonary hypertension (PPH) ECMO also investigated. Logistic regression (LR) decision tree (DTA) performed. 55 included, whom 41 (74.5%) survived. At LR, higher z-Score (ZS) associated lower [OR 0.34 (95% CI 0.14–0.82)], independently from o/eLHR [1.14 (1-03 – 1.25)] a comparable area under de curve (AUC) (0.73 vs. 0.83, p = 0.39). According DTA, best initial predictor mortality an IPaDZS >1.86, 22% In cases < 1.86, second-best o/eLHR. our series, 57% had PPH, 19% underwent ECMO. No found these. ZS predicts improves clinical prediction algorithm cases. There no association morbidity parameters. Supporting Information Please note: publisher is not responsible for content or functionality any supporting information supplied by authors. Any queries (other than missing content) should be directed corresponding author article.