Three‐dimensional power Doppler angiography in endometrial cancer: correlation with tumor characteristics

• DOI: 10.1002/uog.7633
• Publication Date: 2010-03-24T11:18:03Z
• Authors: R. Galván; L. Mercé; M. Jurado; J. Á. Mínguez; G. López‐García; J. L. Alcázar
• Keywords: Adult; Aged, 80 and over; Neovascularization, Pathologic; Angiography; Middle Aged; Endometrial Neoplasms; 3. Good health; 03 medical and health sciences; Imaging, Three-Dimensional; 0302 clinical medicine; Endometrial cancer; Lymphatic Metastasis; Uterine Neoplasms; Humans; Female; Histological characteristics; Ultrasonography, Doppler, Color; Three-dimensional ultrasound; Aged; Neoplasm Staging

To assess the correlation between intratumoral vascularization using three-dimensional power Doppler angiography (3D-PDA) and several histological tumor characteristics in a series of patients with endometrial carcinoma.Ninety-nine women (mean age, 61.7 (range, 31-84) years) diagnosed as having cancer were assessed by transvaginal 3D-PDA before surgical staging. Endometrial volume (EV) vascular indices (vascularization index (VI), flow (FI) (VFI)) calculated Virtual Organ Computer-aided AnaLysis (VOCAL) method. All surgically staged. Individual features such type, grade, myometrial infiltration depth, lymph-vascular space involvement, cervical lymph node metastases stage considered for analysis. Multivariate logistic regression (MLR) analysis was used to determine which parameters independently associated each characteristic.MLR showed that only EV VI (EV: odds ratio (OR), 1.119 (95% CI, 1.025-1.221), P = 0.012; VI: OR, 1.127 1.063-1.195), 0.001) 1.103 1.012-1.202), 0.025; 1.120 1.057-1.187), 0.001), grade (OR, 1.056 1.023-1.091), 1.086 1.017-1.161), 0.001).3D-PDA correlates some prognostic characteristics.