Stabilization of HIV/AIDS model by receding horizon control

• DOI: 10.1007/bf02936558
• Publication Date: 2008-08-14T16:34:22Z
• Authors: A. M. Elaiw; K. Kiss; M. A. L. Caetano
• Keywords: Theory of computation; Feedback Control

This work concerns the stabilization of uninfected steady state of an ordinary differential equation system modeling the interaction of the HIV virus and the immune system of the human body. The control variable is the drug dose, which, in turn, affects the rate of infection of CD4+ T cells by HIV virus. The feedback controller is constructed by a variant of the receding horizon control (RHC) method. Simulation results are discussed.