Efficient strategy for controlling postoperative hemorrhage in total knee arthroplasty

• DOI: 10.1007/s00167-010-1263-5
• Publication Date: 2010-09-17T19:34:52Z
• Authors: Hideyuki Sasanuma; Hitoshi Sekiya; Kenzou Takatoku; Hisashi Takada; Naoya Sugimoto; Yuichi Hoshino
• Keywords: Autologous blood; Group B

The objective of the present study was to compare intraoperative use tranexamic acid (TNA) plus intra-articular diluted-epinephrine (DEP) with preoperative autologous blood donations and transfusions in reducing an allogeneic transfusion (ABT) primary unilateral total knee arthroplasty (TKA).Patients (n=133) treated TKA were divided into three groups retrospectively: patients administered assigned group A (n=51); injections TNA postoperative DEP B (n=42); drain-clamp method addition C (n=40). rate avoidance ABTs, loss, complications (DVT/PE, skin problems) examined.The differences among not significant terms proportion requiring no ABTs (94% A, 93% 95% C, n.s.). loss calculated 1,140±451 ml, 852±343 850±296 respectively (group B>A, C>A, P=0.0009). observed groups.The results showed that combination exerted a comparable effect avoiding TKA. Considering several problems donation, is recommended. In addition, it highly possible can be avoided for Hb values≥10.5 using described this study, need decreased.