A first reported case of clear cell carcinoma associated with delayed extrusion of midurethral tape

• DOI: 10.1007/s00192-015-2876-5
• Publication Date: 2015-11-20T02:15:10Z
• Authors: Harvard Zhenjia Lin; Fiona Meiwen Wu; Jeffrey Jen Hui Low; Kotamma Venkatesw...; Roy Kwok Weng Ng
• Keywords: Suburethral Slings; 03 medical and health sciences; Vaginal Neoplasms; 0302 clinical medicine; Humans; Female; Middle Aged; Adenocarcinoma, Clear Cell; 3. Good health

We present the first reported case of clear cell carcinoma associated with a midurethral tape (MUT), the possible hypotheses and the management pitfalls we encountered. We report a 58-year-old woman who presented with symptoms of urinary tract infection and acute retention of urine associated with vaginal tape exposure 10 years after placement of an inside-out transobturator tape. She subsequently had a partial transobturator tape excision and a diagnostic cystoscopy, which revealed inflammatory changes within the urethra. Postoperatively, her symptoms persisted and the vaginal epithelium healed poorly. A biopsy of the friable tissue reported clear cell carcinoma. Imaging showed a locally invasive periurethral mass and bony and lymphatic metastases. This was treated with palliative radiation therapy. She was still receiving palliative care 5 months after the initial surgery.