Reversal of Pulmonary Hypertension Associated with Plexiform Lesions in Congenital Heart Disease: A Case Report

• DOI: 10.1007/s00246-001-0044-9
• Publication Date: 2002-08-25T02:16:17Z
• Authors: C.L. Epting; R.R. Wolfe; S.H. Abman; G.H. Deutsch; D. Ivy
• Keywords: Ductus arteriosus; Lung biopsy; Vascular surgery

We describe a 2-year-old child with severe pulmonary hypertension due to a patent ductus arteriosus (PDA) with plexiform lesions on lung biopsy. Despite high basal pulmonary vascular resistance with minimal responsiveness to inhaled nitric oxide and other vasodilators, and advanced plexogenic arteriopathy on lung biopsy, her pulmonary hypertension completely resolved after PDA ligation and during 8 years of follow-up.