Feasibility of an Individualized Exercise Training Program for Children with Hypertrophic Cardiomyopathy

• DOI: 10.1007/s00246-025-03843-3
• Publication Date: 2025-04-15T18:28:13Z
• Authors: Julianne Wanner; Danielle Burstein; Stephen Paridon; Maully Shah; Shannon O’Malley; Kimberly Y. Lin; Jonathan B. Edelson
• Keywords: Aerobic Exercise

Abstract Limited data exist to guide exercise participation in pediatric hypertrophic cardiomyopathy (HCM) patients. Exercise is traditionally restricted this population, despite research adults with HCM demonstrating exercise-associated cardiovascular and psychological benefit. This pilot study seeks assesses the safety feasibility of a moderate-intensity program children future design. Eight subjects ages 8–18 were recruited from outpatient cardiology clinic at large tertiary care referral center. All NYHA Class I ( n = 4) or II median septal wall thickness was 2.3 cm [IQR 1.4, 2.5]. The intervention included 16-week program, consisting three 30-min aerobic two strength sessions per week. A target heart rate zone established using baseline cardiopulmonary test (CPET). FitBit device used titrate activity during sessions. Self-reported adherence ranged 1.25 96.25%. At baseline, cardiorespiratory fitness, assessed by CPET, Health Related Quality Life (HRQoL), validated instruments, reduced compared peers. who completed improved performance HRQoL measures. Ambulatory rhythm monitoring did not reveal any intervention-related arrhythmias, there no cardiac adverse events. shows promise potential benefit an interventional HCM. Future work should aim improve retention, more fully assess impact