Comparative analysis of robot-assisted and open approach for PSMA-radioguided surgery in recurrent prostate cancer

• DOI: 10.1007/s00259-023-06460-5
• Publication Date: 2023-10-13T07:02:26Z
• Authors: Francesca Ambrosini; Fabian Falkenbach; Lars Budäus; Thomas Steuber; Markus Graefen; Daniel Koehler; Sophie Knipper; Tobias Maurer
• Keywords: Open surgery

Abstract Purpose To compare the oncological and surgical outcomes of patients with recurrent prostate cancer (PCa) who underwent either open or newly established robot-assisted salvage prostate-specific membrane antigen–radioguided surgery (PSMA-RGS). Materials methods Patients consecutively PSMA-RGS for PCa recurrence between January 2021 December 2022 were identified. The rate complete biochemical response, recurrence-free survival [BFS], therapy evaluated. Univariable multivariable regression models tested association approach outcomes. Results Overall, 85 selected, 61 (72%) undergoing 24 (28%) receiving a approach. two groups comparable (12-month BFS: 41% (Confidence interval (CI): 29–58%) vs. 39% (CI: 19–79%), p = 0.9, respectively). According to models, robotic did not significantly influence estimated blood loss (EBL) ( β −40, 95% CI: −103, 22; 0.2) increased operative time (OT) 28, 10, 46; 0.002). No Clavien-Dindo III–V complications reported in group. Conclusion Both, as well had safety concerns arose robotic-assisted offering potentially improved quality life patients.