Assessment of pelvic organ prolapse with the Pelvic Inclination Correction System: defining the normal range and threshold to pathology

• DOI: 10.1007/s00261-024-04222-x
• Publication Date: 2024-03-13T20:57:50Z
• Authors: Soleen Ghafoor; Stephan Beintner-...; Cornelia Betschart; Thomas Winklehner; Cäcilia S. Reiner
• Keywords: Rank correlation

Abstract Purpose To define the normal range and threshold values for pathologic prolapse on MRI using PICS line assess its correlation with pubococcygeal (PCL). Methods This prospective, IRB-approved study included 20 nulliparous volunteers 18 patients (POP-Q Stage ≥ 2). Organ positions (bladder, cervix, anorectal junction) relative to PCL were measured dynamic MRI. Differences in organ position compared. Receiver-operating characteristic (ROC) analysis was performed identify cutoff line. The between measurements tested Spearman’s rank correlation. Results In volunteers, median bladder cervix at rest − 2.7 cm 5.3 compared 1.9 ( p < 0.001). During straining, 0.9 3.2 versus + 2.5 Correlation strong all three compartments δ = 0.883–0.970, ≤ AUCs of anterior middle compartment 0.98 (95% confidence interval [CI] 0.96–1.00, 0.001) 0.96 CI 0.89–1.00, differentiating from healthy volunteers. AUC posterior 0.76 0.57–0.96, 0.034). Conclusion reliably differentiate compartment. Future studies need a reliable are strongly correlated. Graphical abstract