Musculoskeletal infections caused by streptococcus infantarius – a case series and review of literature

• DOI: 10.1007/s00264-025-06487-3
• Publication Date: 2025-03-13T05:34:38Z
• Authors: Alberto Alfieri Z...; Julian Voss; Alexander Franz; Jonas Roos; Gunnar Thorben Re...; Ernst Molitor; Frank Sebastian F...
• Keywords: Spondylodiscitis

Abstract Purpose The full spectrum of diseases caused by S. infantarius remains poorly understood, particularly its role in musculoskeletal infections. Methods A retrospective study was conducted from January 2008 to May 2024. Patients with bacterial infections and detection at least one tissue sample, fluid or blood cultures were included. Follow-up controls patients infection performed. Results could be identified sample (blood cultures, wound fluid, swab, bile, urine sample) 72 patients. 33 considered clinically relevant symptomatic (63.4 ± 21.1 years; positive samples: 1.39 0.86; total number 2.7 1.76). Non-muskuloskeletal ( n = 29; 61.1 21.5 1.28 0.59) included a variety different (sepsis 11), abdominal/gastrointestinal/urogenital 16), soft 2)). Four (positive 2.25 1.89; diagnosis: acute PJI, spondylodiscitis, chronic PJI postoperative spinal infection) required surgical and/or antimicrobial treatment. after varied between 10 60 months. Antibiotic susceptibility testing displayed sensitivity Penicillin all isolates. No patient had recurrent sample/infection . Conclusions This describes , highlighting possible relevance as pathogen orthopedic findings underscore the importance recognizing appropriately treating In case penicillin allergy, clindamycin shows an effective alternative