Diagnosis and Management of Male Breast Cancer
Aged, 80 and over
Male
Antineoplastic Agents
Middle Aged
Breast Neoplasms, Male
3. Good health
Cohort Studies
Survival Rate
03 medical and health sciences
Carcinoma, Intraductal, Noninfiltrating
Sex Factors
0302 clinical medicine
Chemotherapy, Adjuvant
Humans
Radiotherapy, Adjuvant
Mastectomy
Aged
Retrospective Studies
DOI:
10.1007/s00268-008-9713-7
Publication Date:
2008-09-11T12:11:55Z
AUTHORS (7)
ABSTRACT
AbstractBackgroundMale breast cancer (MBC) is rare with an incidence of 1% of all breast cancers. The evidence about the treatment is derived from the data on the management of the female breast cancer because conduction of randomized, controlled trials is impossible due to the rarity of the disease. In this study, we review the special features, overall management, diagnosis, and treatment of patients with MBC managed under our care with a brief review of the current literature.MethodsDuring the period 1998 to 2006, we managed 1103 new patients with breast cancer in St Mary’s Hospital. Among these, 14 patients were men. We retrospectively reviewed the case notes, histology, and follow‐up notes of all the newly diagnosed patients with MBC.ResultsIn this series, 28.6% had only in situ disease. Moreover, in 78.6% there was an in situ component present. One patient was found to have a cancer on the microdochectomy specimen after an operation for single duct nipple discharge, and in a second patient the cancer was found in the gynecomastia operation specimen. All ten invasive tumors were estrogen receptor positive (ER +ve), whereas eight were progesterone receptor positive (PgR +ve). With a median follow‐up of 35 months, there was one locoregional recurrence and one disease‐associated death.ConclusionsIn situ cancer may not be as rare as previously reported among patients with MBC. Increased patient awareness and early assessment by a specialist is a key to early diagnosis and improved outcomes.
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