Quantitative and qualitative assessment of non-contrast-enhanced pulmonary MR imaging for management of pulmonary nodules in 161 subjects

• DOI: 10.1007/s00330-008-1001-2
• Publication Date: 2008-05-05T09:19:00Z
• Authors: Hisanobu Koyama; Yoshiharu Ohno; Atsushi Kono; Daisuke Takenaka; Yoshimasa Maniwa; Yoshihiro Nishimura; Chiho Ohbayashi; Kazuro Sugimura
• Keywords: Adult; Aged, 80 and over; Male; Lung Neoplasms; Contrast Media; Reproducibility of Results; Middle Aged; Magnetic Resonance Imaging; Sensitivity and Specificity; 3. Good health; Radiographic Image Enhancement; 03 medical and health sciences; 0302 clinical medicine; Humans; Multiple Pulmonary Nodules; Radiographic Image Interpretation, Computer-Assisted; Female; Tomography, X-Ray Computed; Aged

This study aimed at prospectively compared efficacy of non-contrast-enhanced (non-CE) MRI and MDCT for management of pulmonary nodules. A total of 161 patients with 200 nodules underwent MDCT and non-CE MRI (T1WI, T2WI, and STIR) in conjunction with pathological and/or more than 2 years of follow-up examinations. To compare qualitative detection rates between both modalities, all nodules were visually assessed. To compare quantitative and qualitative diagnostic capabilities of MRI, calculation of contrast ratio and visual assessment of probability for malignancy in each nodule were performed. Then, detection rate and diagnostic capability were statistically compared. Although the overall detection rate of each MR sequence (82.5%) was significantly lower than that of MDCT (97.0%, p<0.05), that of malignant nodules showed no significant difference (p>0.05). The diagnostic capability of STIR was significantly higher than those of other MR sequences (p<0.05). Non-CE MR imaging was found to be as useful as MDCT for management of pulmonary nodules.