Breast cancer screening in women with extremely dense breasts recommendations of the European Society of Breast Imaging (EUSOBI)

• DOI: 10.1007/s00330-022-08617-6
• Publication Date: 2022-03-08T10:02:51Z
• Authors: Ritse M. Mann; Alexandra Athanasiou; Pascal A. T. Baltzer; Julia Camps-Herrero; Paola Clauser; Eva M. Fallenberg; Gabor Forrai; Michael H. Fuchsj...; Thomas H. Helbich; Fleur Killburn-To...; Mihai Lesaru; Pietro Panizza; Federica Pediconi; Ruud M. Pijnappel; Katja Pinker; Francesco Sardanelli; Tamar Sella; Isabelle Thomassi...; Sophia Zackrisson; Fiona J. Gilbert; Christiane K. Kuhl
• Keywords: Radboudumc 17: Women's cancers RIHS: Radboud Institute for Health Sciences; Breast Neoplasms; 03 medical and health sciences; Magnetic resonance imaging; 0302 clinical medicine; breast density; decision-making, shared; early detection of cancer; magnetic resonance imaging; mammography; Early detection of cancer; shared; Medical Imaging - Radboud University Medical Center; Breast density; Humans; Mass Screening; Female; Breast; Early Detection of Cancer; Decision-making; Breast Density; Mammography

Abstract Breast density is an independent risk factor for the development of breast cancer and also decreases the sensitivity of mammography for screening. Consequently, women with extremely dense breasts face an increased risk of late diagnosis of breast cancer. These women are, therefore, underserved with current mammographic screening programs. The results of recent studies reporting on contrast-enhanced breast MRI as a screening method in women with extremely dense breasts provide compelling evidence that this approach can enable an important reduction in breast cancer mortality for these women and is cost-effective. Because there is now a valid option to improve breast cancer screening, the European Society of Breast Imaging (EUSOBI) recommends that women should be informed about their breast density. EUSOBI thus calls on all providers of mammography screening to share density information with the women being screened. In light of the available evidence, in women aged 50 to 70 years with extremely dense breasts, the EUSOBI now recommends offering screening breast MRI every 2 to 4 years. The EUSOBI acknowledges that it may currently not be possible to offer breast MRI immediately and everywhere and underscores that quality assurance procedures need to be established, but urges radiological societies and policymakers to act on this now. Since the wishes and values of individual women differ, in screening the principles of shared decision-making should be embraced. In particular, women should be counselled on the benefits and risks of mammography and MRI-based screening, so that they are capable of making an informed choice about their preferred screening method.

Key Points • The recommendations in Figure 1 summarize the key points of the manuscript