Long-term outcomes of left bundle branch area pacing versus biventricular pacing in patients with heart failure and complete left bundle branch block

• DOI: 10.1007/s00380-021-02016-5
• Publication Date: 2022-01-28T03:03:27Z
• Authors: Juan Hua; Yang Chen; Jianhua Yu; Qinmei Xiong; Zhen Xia; Zirong Xia; Qianghui Huang; Qiling Kong; Huolong Chen; Yichu Zhang; Jianxin Hu; Juxiang Li; Jinzhu Hu; Qi Chen; Kui Hong
• Keywords: Bundle branch block

Left bundle branch area pacing (LBBAP) has developed in an effort to improve cardiac resynchronization therapy (CRT). We aimed compare the long-term clinical outcomes between LBBAP and biventricular (BIVP) patients with heart failure (HF) complete left block (CLBBB). Consecutive HF CLBBB requiring CRT received either or BIVP were recruited at Second Affiliated Hospital of Nanchang University from February 2018 May 2019. assessed their implant parameters, electrocardiogram (ECG), during follow-up 1, 3, 6, 12, 24 months. Forty-one including 21 for 20 BIVP. Mean duration was 23.71 ± 4.44 produced lower thresholds, shorter procedure time fluoroscopy compared The QRS significantly narrower after than (129.29 31.46 vs. 156.85 26.37 ms, p = 0.005). Notably, both improved LVEF, LVEDD, NYHA class, BNP baseline. However, lowered (416.69 411.39 96.07 788.71 pg/ml, 0.007) baseline 24-month follow-up. Moreover, who exhibited number hospitalizations those group (p 0.019). In addition, we found that moderately prolonged ventricular activation (LVAT) notching limb leads ECG respond better correction. might be a relative safe effective as supplement CLBBB.