Lateral ventricle meningiomas in children: clinicopathological and neuroradiological features

• DOI: 10.1007/s00381-022-05680-8
• Publication Date: 2022-11-01T02:02:34Z
• Authors: Yufan Chen; Shuaiwei Tian; Jiajia Wang; Zhuangzhuang Liang; Baocheng Wang; Yang Zhao; Jie Ma
• Keywords: Adult; Male; Cysts; Choristoma; Magnetic Resonance Imaging; 03 medical and health sciences; 0302 clinical medicine; Child, Preschool; Lateral Ventricles; Meningeal Neoplasms; Humans; Edema; Female; Child; Meningioma; Retrospective Studies; Hydrocephalus

Lateral ventricle meningiomas (LVM) in children are very rare. The current research is mostly limited to adults, and there are very few related studies on children. The purpose of this study was to analyze the clinicopathological and imaging features of lateral ventricle meningiomas in children.A retrospective analysis of five children with pathologically confirmed lateral ventricle meningioma was performed, and we collected clinical data, including clinicopathological data, treatment prognosis data, and imaging features (including tumor location, signal intensity, enhancement degree, intratumoral cyst, calcification, peritumoral edema, and associated hydrocephalus).Among the 5 patients with LVM, 4 were male and 1 was female with an average age of 7.6 years (range 2 to 12 years). All CT scans showed slight hyperintensity or isodensity, and only 1 patient had calcification. Two patients demonstrated cyst changes. Four patients had varying degrees of peritumoral edema. The average tumor volume was 164.1 cm3 (1.4-314.9 cm3). All 5 patients with LVM were iso- or hypointense on T1WI. The T2WI signals had no obvious features. Four patients had a high signal on DWI (80%). The contrast-enhanced signals were mostly homogeneously strong (80%). MRI showed hydrocephalus in 3 patients. All patients underwent gross total resection, and they were followed up regularly after the operation. The average follow-up time was 47.4 months. No recurrence was found in any of the children. All patients were pathologically confirmed to have meningiomas, and WHO grades were all grade I.Lateral ventricle meningiomas in children are very rare, and the imaging manifestations of the tumor have certain characteristics, but the clinical diagnosis is still difficult, and the diagnosis still requires pathological analysis.