Mode of presentation and mortality amongst patients hospitalized with heart failure? A report from the First Euro Heart Failure Survey

• DOI: 10.1007/s00392-018-1380-6
• Publication Date: 2018-10-25T11:03:35Z
• Authors: Ahmad Shoaib; M. Farag; J. Nolan; A. Rigby; A. Patwala; M. Rashid; C. S. Kwok; R. Perveen; A. L. Clark; M. Komajda; J. G. F. Cleland
• Keywords: Etiology; Presentation (obstetrics)

Heart failure is heterogeneous in aetiology, pathophysiology, and presentation. Despite this diversity, clinical trials of patients hospitalized for HF deal with problem as a single entity, which may be one reason repeated failures. The first EuroHeart Failure Survey screened consecutive deaths discharges suspected heart during 2000–2001. Patients were sorted into seven mutually exclusive hierarchical presentations: (1) cardiac arrest/ventricular arrhythmia; (2) acute coronary syndrome; (3) rapid atrial fibrillation; (4) breathlessness; (5) other symptoms/signs such peripheral oedema; (6) stable symptoms; (7) others whom the contribution to admission was not clear. 10,701 enrolled classified above presentations follows: 260 (2%), 560 (5%), 799 (8%), 2479 (24%), 1040 (10%), 703 (7%), 4691 (45%) index-admission mortality 26%, 20%, 10%, 8%, 6%, 4%, respectively. Compared those group 7, hazard ratios death index 4.9 (p ≤ 0.001), 4.0 < 2.2 2.1 1.4 0.04) = 0.04), These differences no longer statistically significant by 12 weeks. There great diversity presentation that associated very different short-term outcomes. Only minority hospitalizations are breathlessness. This should taken account design future trials.