Minimally invasive stereotactic puncture and thrombolysis therapy improves long-term outcome after acute intracerebral hemorrhage

• DOI: 10.1007/s00415-011-5902-7
• Publication Date: 2011-02-21T02:12:28Z
• Authors: Houguang Zhou; Yu Zhang; Ling Liu; Yanyan Huang; Yuping Tang; Jingjing Su; Wei Hua; Xu Han; Jianzhong Xue; Qiang Dong
• Keywords: Glasgow Outcome Scale; Case fatality rate; Coma (optics)

The purpose of this study was to judge the clinical value minimally invasive stereotactic puncture and thrombolysis therapy (MISPTT) for acute intracerebral hemorrhage (ICH). A randomized control trial undertaken. According enrollment criteria, 122 ICH cases were analyzed, which 64 received MISPTT (MISPTT group, MG) 58 conventional craniotomy (CC CG). Glasgow coma scale (GCS) scores, postoperative complications (PC), rebleeding incidences compared. Moreover, 1 year postoperation, long-term outcomes patients with regard hematoma volume (HV) <50 mL HV ≥50 judged, respectively, by outcome (GOS), Barthel index (BI), modified Rankin Scale (mRS), case fatality (CF). MG showed obvious amelioration in GCS score compared that CG patients. total incidence PC decreased CG. 9.4 17.2%, respectively (P = 0.243). There no differences between CFs (17.2 25.9%, P 0.199). GOS, BI, mRS representing both ameliorated significantly greater than (all < 0.05). These data suggest there are advantages not only trauma safety, but group had fewer a trend toward improved short-term outcomes.