Evaluation of a self-administered iPad®-based processing speed assessment for people with multiple sclerosis in a clinical routine setting

• DOI: 10.1007/s00415-024-12274-8
• Publication Date: 2024-03-05T08:02:02Z
• Authors: Stefanie Hechenbe...; Birgit Helmlinger; Christian Tinauer; Emanuel Jauk; Stefan Ropele; Bettina Heschl; Sebastian Wurth; Anna Damulina; Sebastian Eppinger; Rina Demjaha; Michael Khalil; Christian Enzinger; Daniela Pinter
• Keywords: Cognitive Assessment System

Abstract Background Limited resources often hinder regular cognitive assessment of people with multiple sclerosis (pwMS) in standard clinical care. A self-administered iPad®-based screening-tool (Processing Speed Test; PST) might mitigate this problem. Objective To evaluate the PST routine. Methods We investigated feasibility both a quiet and waiting room setting. assessed validity comparison established Symbol Digit Modalities Test (SDMT). explored associations between processing speed assessments Brief International Cognitive Assessment for MS (BICAMS), magnetic resonance imaging (MRI) parameters, psychological factors. Additionally, we ability to detect impairment compared SDMT. Results The was feasible SDMT correlated comparably BICAMS, MRI variables. Of 172 pwMS, 50 (30.8%) showed according BICAMS; respective values were 47 (27.3%) 9 (5.2%) PST. Conclusions performed setting correlates strongly tests. It thus may be used assess resource-efficient manner complement Despite comparable SDMT, identified more pwMS impaired using normative data advise caution, that common cut-off score – 1.5 SD from current is not appropriate Europe.