Clinical and neuroanatomical characterization of the semantic behavioral variant of frontotemporal dementia in a multicenter Italian cohort

• DOI: 10.1007/s00415-024-12338-9
• Publication Date: 2024-04-10T11:01:46Z
• Authors: Alma Ghirelli; Edoardo Gioele Sp...; Elisa Canu; Silvia Basaia; Veronica Castelnovo; Giordano Cecchetti; Elisa Sibilla; Teuta Domi; Giuseppe Magnani; Francesca Caso; Paola Caroppo; Sara Prioni; Cristina Villa; Giacomina Rossi; Lucio Tremolizzo; Ildebrando Appoll...; Federico Verde; Nicola Ticozzi; Vincenzo Silani; Massimo Filippi; Federica Agosta
• Keywords: Semantic dementia; Neuroradiology; Frontotemporal lobar degeneration

Semantic behavioral variant frontotemporal dementia (sbvFTD) is a neurodegenerative condition presenting with specific and semantic derangements predominant atrophy of the right anterior temporal lobe (ATL). The objective was to evaluate clinical, neuropsychological, neuroimaging, genetic features an Italian sbvFTD cohort, defined according recently proposed guidelines, compared primary progressive aphasia (svPPA) FTD (bvFTD) patients.