Screening for functional gastrointestinal disorders in preterm infants up to 12 months of corrected age: a prospective cohort study

• DOI: 10.1007/s00431-024-05451-4
• Publication Date: 2024-02-12T17:02:22Z
• Authors: Yusuf Aydemir; Ozge Aydemir; Meltem Dinleyici; Adviye Cakil Saglik; Demet Cam; Tugba Barsan Kaya; Fuat Emre Canpolat
• Keywords: Infantile colic

Abstract Functional gastrointestinal disorders (FGIDs) are characterized by a variety of symptoms that frequently age-dependent, chronic, or recurrent and not explained structural biochemical abnormalities. There studies in the literature reporting different results regarding relationship between prematurity FGIDs. The main objective this study was to compare frequency FGIDs preterm term infants. secondary evaluate whether there any association neonatal characteristics development A multicenter prospective cohort included infants born before 37 weeks gestation healthy carried out. At 1, 2, 4, 6, 9, 12 months age, were assessed for presence using Rome IV criteria. In infants, an additional follow-up visit made at corrected age. 134 104 enrolled study. Infantile colic, rumination syndrome, functional constipation, infant dyschezia more common Incidence other (infant regurgitation, diarrhea cyclic vomiting syndrome) similar among Preterm who exclusively breastfeed first 6 life have lower incidence infantile colic (18.8% vs 52.1%, p = 0.025). terms chronological started later infants; difference statistically significant regurgitation (median age 2 1 month, < 0.001). Conclusions : higher prevalence compared with controls. Therefore, especially if they complaints, should be screened Possibly due maturational differences, time occurrence may differ decreases exclusive breastfeeding. What is Known: • very infancy. Data on currently limited. New: constipation when breastfed during experience colic.