Macrolide-resistant Mycoplasma pneumoniae is an independent risk factor for bronchial mucus plug formation in children

• DOI: 10.1007/s00431-025-06095-8
• Publication Date: 2025-03-24T03:49:49Z
• Authors: Xie Chunlian; Zhou Lili; Zhang Libin; Xiao Yichun

This study aimed to explore the characteristics of bronchial mucus plug formation and its risk factors. A total 578 children who underwent bronchoalveolar lavage treatment between January 2022 June 2024 at Department Pediatric, Women Children's Hospital Ganzhou were assessed in this study.The fluid was tested by next-generation sequencing. The resistance genes macrolides Mycoplasma pneumoniae (MP) detected polymerase chain reaction. Data related basic information, clinical characteristics, etiology statistically analyzed. Logistic regression analysis performed identify independent factors for formation. There 312 cases group 266 non-mucus group. older, had longer hospital stays, exhibited a higher incidence fever, experienced more complications, rates hormone use when compared those (P < 0.05). detection rate MP macrolide significantly than According logistic analysis, macrolide-resistant (MRMP) acted as an factor plugs children. Conclusion: Bronchial common with infection, often accompanied fever prolonged hospitalization. MRMP thus identified