Laparoscopic partial versus radical nephrectomy for localized renal cell carcinoma over 4 cm

• DOI: 10.1007/s00432-023-05487-3
• Publication Date: 2023-11-09T05:01:36Z
• Authors: Zi-Jun Sun; Feng Liu; Hai-Bin Wei; Da-Hong Zhang
• Keywords: Nephrology

To compare the long-term clinical and oncologic outcomes of laparoscopic partial nephrectomy (LPN) radical (LRN) in patients with renal cell carcinoma (RCC) > 4 cm.We retrospectively reviewed records all who underwent LPN or LRN our department from January 2012 to December 2017. Of 151 met study selection criteria, 54 received LPN, 97 LRN. After propensity-score matching, 51 matched pairs were further analyzed. Data on patients' surgical data, complications, histologic function, survival collected analyzed.Compared group, group had a longer operative time (135 min vs. 102.5 min, p = 0.001), larger intraoperative bleeding (150 ml 50 ml, < required stays hospital (8 days 6 days, 0.001); however, level ECT-GFR was superior at 3, 6, 12 months (all 0.001). Similarly, greater number developed CKD compared until postoperative (58.8% 19.6%, In preoperative CKD, may delay progression stage even improve it when treatment. There no significant differences between two groups for OS, CSS, MFS, PFS (p 0.06, 0.30, 0.90, 0.31, respectively). The method not be risk factor prognosis.LPN preserves function better than has potential value significantly reducing but prognosis is comparable.