Assessment of long-term renal complications in extremely low birth weight children

• DOI: 10.1007/s00467-011-1840-y
• Publication Date: 2011-04-02T06:16:11Z
• Authors: Przemko Kwinta; Małgorzata Klimek; Dorota Drozdz; Andrzej Grudzień; Mateusz Jagła; Magdalena Zasada; Jacek Jozef Pietrzyk
• Keywords: Nephrology

We assessed the long-term renal complications in a regional cohort of extremely low birth weight (ELBW) children born 2002-2004. The study group, comprising 78 as ELBW infants (88% available cohort), was evaluated with measurement serum cystatin C, urinary albumin excretion, ultrasound, and 24-h ambulatory blood pressure measurements. control group included 38 full-term selected from one general practice district. Study patients were at mean age 6.7 years, had median birthweight 890 g (25th-75th percentile: 760-950 g) gestational 27 weeks 26-29 weeks). Mean C levels significantly higher (0.64 vs. 0.59 mg/l; p = 0.01) group. Hypertension diagnosed 8/78 2/38 (p 0.5). Microalbuminuria (>20 mg/g creatinine) detected only five 0.17). volume lower (absolute kidney 81 ml 113 ml; < 0.001, relative 85 97%; 0.001). Abnormally small kidneys (<2/3 predicted size) 19 four 0.08). Multivariate logistic regression revealed that independent risk factor for gained during neonatal hospitalization (odds ratio: 0.67; 95% confidence interval: 0.39-0.94). Serum are school-age children. It is important to include systematic evaluation follow-up programs infants.