The relationship between diabetes and clinical outcomes in COVID-19: a single-center retrospective analysis

• DOI: 10.1007/s00592-020-01592-8
• Publication Date: 2020-08-17T10:03:10Z
• Authors: Tamaryn Fox; Kathleen Ruddiman; Kevin Bryan Lo; Eric Peterson; Robert DeJoy; Grace Salacup; Jerald Pelayo; Ruchika Bhargav; Fahad Gul; Jeri Albano; Zurab Azmaiparash...; Catherine Anastas...; Gabriel Patarroyo...
• Keywords: 2019-20 coronavirus outbreak; Center (category theory)

Coronavirus disease 19 (COVID-19) has become a pandemic. Diabetic patients tend to have poorer outcomes and more severe (Kumar et al. in Diabetes Metab Syndr 14(4):535-545, 2020. https://doi.org/10.1016/j.dsx.2020.04.044 ). However, the vast majority of studies are representative Asian Caucasian population fewer represent an African-American population.In this single-center, retrospective observational study, we included all adult (> 18 years old) admitted Einstein Medical Center, Philadelphia, with diagnosis COVID-19. Patients were classified according having known diabetes mellitus. Demographic clinical data, comorbidities, laboratory findings obtained.Our sample total 355 patients. 70% African-American, 47% had diabetes. higher peak inflammatory markers like CRP 184 (111-258) versus 142 (65-229) p = 0.012 LDH 560 (384-758) 499 (324-655) 0.017. The need for RRT/HD was significantly (21% vs 11% 0.013) as well vasopressors (28% 18% 0.023). Only age found be independent predictor mortality. We no significant differences inpatient mortality 0.856, 0.429, intubation 1.000 0.471 African-Americans when compared non-African-Americans.Our study demonstrates that COVID-19 outcomes. did not differ or severity non-African-American