Uricase based methods for determination of uric acid in serum

• DOI: 10.1007/s00604-008-0044-z
• Publication Date: 2008-05-08T06:50:22Z
• Authors: Yunsheng Zhao; Xiaoyan Yang; Wei Lu; Hong Liao; Fei Liao
• Keywords: Allantoin; Urate Oxidase; Nanochemistry

The most common methods for determination of uric acid in serum are based on the use of the enzyme uricase. Uric acid is enzymatically oxidized by oxygen to produce hydrogen peroxide, allantoin, and carbon dioxide. The four most often applied uricase methods are critically compared in this review.