In vivo 9.4 Tesla MRI of a patient with drug-resistant epilepsy: Technical report

• DOI: 10.1007/s00701-024-06385-4
• Publication Date: 2025-01-16T06:37:09Z
• Authors: Rick H. G. J. van...; Daniel Uher; Desmond H. Y. Tse; Esther Steijvers; Albert J. Colon; Jacobus F. A. Jansen; Gerhard S. Drenthen; Dimo Ivanov; Govert Hoogland; Kim Rijkers; Christianne M. Ho...; Paul A. M. Hofman; Walter H. Backes; Olaf E. M. G. Sch...
• Keywords: Neuroradiology; Interventional radiology; Drug Resistant Epilepsy

In resective epilepsy surgery for drug-resistant focal (DRE), good seizure outcome is strongly associated with visualization of an epileptogenic lesion on MRI. Standard clinical MRI (≤ 3 Tesla (T)) may fail to detect subtle lesions. 7T enhances detection and delineation, the potential benefits increasing field strength 9.4T are explored. A 36 years old male patient DRE evaluated surgery, in which 3T failed any lesions, was submitted a dedicated scan protocol using T1 T2* weighted imaging at 9.4T. Images were independently by two neuroradiologists one neurosurgeon. offered increased spatial resolution enhanced depiction anatomical structures vital imaging, exemplified regions mesio-temporal (hippocampus, amygdala), latero-temporal, insula, frontal temporal operculum, gray-white matter junction (precentral gyrus/frontal lobe) compared 7T, albeit challenges mesial-temporal antero-inferior lobe imaging. No identified. demonstrates promise identification delineation small lesions patients eligible surgery. Whether has advantages over or leads more complete resection zone improved after needs be established.