Armored RNA as positive control and standard for quantitative reverse transcription-polymerase chain reaction assay for rubella virus

• DOI: 10.1007/s00705-006-0839-3
• Publication Date: 2006-09-27T06:10:11Z
• Authors: L. Zhao; Y. Ma; S. Zhao; N. Yang
• Keywords: Rubella virus

RV Armored RNA constructed in the laboratory was shown to be resistant to RNase and DNase digestion. It could remain stable at 4 degrees C for at least 60 days, and was much more stable than RV strain TR23 [corrected] in normal human plasma. Therefore it could be used as stable, well-characterized positive control and standard for quantitative RT-PCR assay.