Porcine-like G3P[6] and G4P[6] rotavirus A strains detected from children with diarrhoea in Vietnam

• DOI: 10.1007/s00705-018-3836-4
• Publication Date: 2018-04-05T10:43:55Z
• Authors: Miho Kaneko; Loan Phuong Do; Yen Hai Doan; Toyoko Nakagomi; Punita Gauchan; Chantal Ama Agbem...; Anh Duc Dang; Osamu Nakagomi
• Keywords: Strain (injury)

Animal rotavirus A (RVA) strains can infect children and cause diarrhoea. We determined the full genome sequences of one G3P[6] strain (NT0001) and five G4P[6] strains (NT0042, NT0077, NT0205, NT0599, and NT0621) detected from children with diarrhoea in Vietnam in 2007-2008. Strain NT0001 had a genotype constellation of: G3-P[6]-I5-R1-C1-M1-A8-N1-T1-E1-H1, strain NT0042: G4-P[6]-I1-R1-C1-M1-A8-N1-T1-E1-H1, strain NT0077: G4-P[6]-I5-R1-C1-M1-A8-N1-T7-E1-H1, and strains NT0205, NT0599, and NT0621: G4-P[6]-I1-R1-C1-M1-A1-N1-T1-E1-H1. Sequence divergence data and phylogenetic analysis showed that they were different porcine RVA strains that independently and directly crossed the host species barrier to infect children.