An arrayed-window microfluidic device for observation of mixed nanoparticles with an X-ray free-electron laser

• DOI: 10.1007/s10043-021-00716-x
• Publication Date: 2022-01-24T00:05:27Z
• Authors: Yutaka Matsumoto; Yoko Takeo; Satoru Egawa; Gota Yamaguchi; Shunya Yokomae; Masashi Takei; Hirokatsu Yumoto; Takahisa Koyama; Haruhiko Ohashi; Kensuke Tono; Makina Yabashi; Hidekazu Mimura; Takashi Kimura
• Keywords: Free-electron laser; Nanometre; Water window; Free electron model

Abstract A microfluidic device was developed for coherent diffraction imaging using an X-ray free-electron laser (XFEL-CDI). Liquid samples, which are separately packed in reservoirs of the device, mixed a flow channel after XFEL irradiation as trigger. An XFEL-CDI experiment conducted and images gold nanoparticles solution were obtained with resolution several nanometers from single-shot patterns. We able to capture various structures channel, clearly demonstrating function device. The direct observation structural changes liquids will contribute development chemistry biology.